Is aspirin an NSAID?

Yes, aspirin is considered a nonsteroidal anti-inflammatory drug (NSAID). The term nonsteroidal distinguishes NSAIDs from another class of anti-inflammatory drugs called steroids, which have a wide range of additional effects within the body. Other examples of NSAIDs available without a prescription include ibuprofen (Motrin, Advil) and naproxen (Aleve). Acetaminophen (Tylenol) is not an NSAID.

Aspirin, like other NSAIDS, inhibits cyclooxygenase (COX), an enzyme in our body that helps to produce prostaglandins. By doing this, aspirin blocks the production of prostaglandins, which are natural chemicals that regulate pain, body temperature and inflammation.

Because of this action, aspirin and other NSAIDs are pain relievers, fever reducers and anti-inflammatories. NSAIDs are also available in prescription-strength formulas. They may be prescribed for treating the pain that comes from inflammation, such as pain associated with arthritis, bursitis and tendonitis.

Updated October 2024.