A middle aged person using tissue paper for his stuffy nose.

Is it RSV, COVID-19, the flu or a common cold? How to prevent and treat

By Christina Varvatsis, PharmD, BCPS Feb 09, 2024 • 6 min


It’s not just flu season anymore. “Respiratory illness season” also brings COVID-19, RSV and the common cold. But because many of these viruses have similar symptoms, it can be hard to know what you may have. Learn more about these common respiratory illnesses, testing options, and what you can do to prevent and treat these conditions. 

Similar symptoms can make it hard to know what you have 

Many respiratory viruses, like the flu, COVID-19, RSV and the common cold share similar symptoms, such as a fever, cough and a runny nose. It’s important to know what symptoms might help your healthcare provider narrow it down (think loss of taste or smell with COVID-19).

 

         RSV

       COVID-19

         Flu

Common cold

Common signs & symptoms

  • Runny nose
  • Decreased appetite
  • Coughing
  • Sneezing
  •  Fever
  •  Wheezing
  •  Fever or chills
  •  Cough
  •  Shortness of breath or difficulty breathing
  •  Fatigue
  •  Muscle or body aches
  •  Headache
  •  New loss of taste or smell
  •  Sore throat
  •  Congestion or runny nose
  •  Nausea or vomiting
  •  Diarrhea
  •  Fever or chills
  •  Cough
  •  Sore throat
  •  Runny or stuffy nose
  •  Muscle or body aches
  •  Headache
  •  Fatigue
  •  Vomiting and diarrhea (more common in children)
  •  Cough
  •  Sneezing
  •  Runny or stuffy nose
  •  Sore throat
  •  Headache
  •  Body aches
  •  Fever

But because these viruses often have overlapping symptoms, testing is the only way to know for sure what you have. 

Testing is available for COVID-19 and flu 

Walgreens offers rapid COVID-19 and flu testing in a single swab, with results available in 30 minutes. Our COVID-19 and flu test checks for both viruses and is available for $19.99 without insurance. You can talk to your pharmacist or find more information about testing options on our website.

Treatment options 

Depending on the illness you have, specific treatments may be available to help reduce your symptoms (another reason to get tested!).

COVID-19

Antiviral medications, such as Paxlovid, may be considered for people at high risk of developing severe COVID-19. Antivirals must be started within five days of when symptoms begin, so be sure to seek treatment as soon as you start to feel unwell.

Walgreens pharmacists can prescribe Paxlovid for eligible individuals. Learn more about this service and find out if you qualify.

Flu

Antiviral medications for the flu, such as Tamiflu, Relenza, Rapivab and Xofluza can lessen symptoms and shorten how long you are sick. Antiviral medications for the flu work best if taken one to two days after symptoms begin. 

General symptom relief

Not sure what you have? These tips can help manage your symptoms no matter the cause.

  • Manage fever and pain with over-the-counter fever and pain relievers, such as acetaminophen or ibuprofen (remember — never give aspirin to children)
  • Clear stuffy noses with saline nasal drops or suctioning (for infants or young children)
  • Stay well hydrated by drinking plenty of fluids
  • Make sure you’re getting enough rest

Vaccines help protect against flu, COVID-19 and RSV 

Getting vaccinated is the best way to help stay protected against these common respiratory viruses.

COVID-19 and flu vaccines are recommended for everyone 6 months and older. Adults 60 and older, along with people who are pregnant, may consider getting the RSV vaccine.

The good news? You can receive more than one vaccine in one visit to Walgreens. We vaccinate everyone age 3 and older, so check out our vaccine scheduler to make your appointment.

Everyday preventive tips to help you stay healthy 

RSV, COVID-19, flu and the common cold all spread when droplets from an infected person’s cough or sneeze enter your body through your nose or mouth (and sometimes eyes).  Because these viruses are transmitted the same way, following a few simple prevention tips can help protect you against all four illnesses. 

In addition to staying up to date on vaccines, be sure to:

  • Wash your hands often with soap and water for at least 20 seconds
  • Avoid touching your eyes, nose or mouth with unwashed hands
  • Clean and disinfect commonly touched surfaces, such as phones, doorknobs and toys
  • Avoid close contact with anyone experiencing symptoms or feeling unwell
  • Consider wearing a mask in crowded indoor settings when respiratory illnesses are high in your community

Don’t forget to shop at Walgreens for all your symptom-relief products.

Published February 2024.

Explore more

6 min
By Christina Varvatsis, PharmD, BCPS
Aug 17
2 min
By Amy Magill, Manager, Office of Clinical Integrity
Aug 24
6 min
By Sonali Kshatriya, PharmD
Mar 10
4 min
By Jenilee Matz, MPH
Aug 25